Cyclamates ban: Carcinogenicity claim questioned

Asbestos findings questioned.

The relationship between autocrine interferon (IFN) production and the expression of class I Major Histocompatibility Complex (MHC) membrane glycoproteins in vitro was investigated in a panel of murine transformed cells of nonhaemopoietic origin. The panel included 11 cell lines of H-2Kb haplotype derived from fibrosarcomas, carcinomas and melanoma, and from transformed fibroblasts. IFN activit...

Key Alzheimer's findings questioned.

When Stephen Strittmatter discovered an unexpected link between key proteins in two devastating brain maladies — Alzheimer’s disease and Creutzfeldt–Jakob disease (CJD) — researchers in the field agreed that he was on to something big. But a year on, conflicting results, including findings published in Nature this month, have clouded that rosy picture and highlight the challenge faced by resear...

Value of e-prescribing questioned.

© 2011 Canadian Medical Association or its licensors CMAJ, October 4, 2011, 183(14) 1575 Decades after Canada’s 33 700 pharmacists began buying computers in the expectation that provincial health systems would connect them with physicians through electronic prescription networks, such information sharing may be inching toward becoming a reality. Although skeptics say the primary rationale for s...

Canada's approach to biosimilars questioned.

To ban or not to ban?

The past four years have seen a steady increase in the number of companies that offer direct-to-consumer (DTC) genetic testing services and in the number of such tests for genetic risk factors, including a wide range of diseases and other non-disease-related traits. These companies sell their tests outside the traditional healthcare setting and often do not involve healthcare professionals for ...